Short-chain perfluoroalkyl acids: environmental concerns and a regulatory strategy under REACH
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چکیده
منابع مشابه
Short-chain perfluoroalkyl acids: environmental concerns and a regulatory strategy under REACH
Background Short-chain PFASs (per- and polyfluoroalkyl substances) are widely used as alternatives to long-chain PFASs. Long-chain PFASs become gradually regulated under REACH (EC No. 1907/2006) and other international regulations, due to having persistent, bioaccumulative and toxic properties and/or being toxic for reproduction. The increasingly used short-chain PFASs are assumed to have a low...
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OBJECTIVES Perfluoroalkyl carboxylic acids (PFCAs) consist of analogs with various carbon chain lengths. Their toxicokinetics have remained unexplored except in the case of perfluorooctanoic acid (8 carbon chemicals). This study aimed to investigate the toxicokinetics of PFCAs with six to fourteen carbon atoms (C6 to C14) in mice and humans. METHODS We applied a two-compartment model to mice ...
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ژورنال
عنوان ژورنال: Environmental Sciences Europe
سال: 2018
ISSN: 2190-4707,2190-4715
DOI: 10.1186/s12302-018-0134-4